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KMID : 0895820090190010073
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Journal of Oriental Rehabilitation Medicine
2009 Volume.19 No. 1 p.73 ~ p.89
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The Effects of Polygonum Cuspidatum on the Skin Functions
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Jung Hyun-A
Roh Seok-Sun
Oh Min-Seok
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Abstract
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Objectives :This study was carried out to investigate the effects of Polygonum cuspidatum extract on several skin functions including inflammation and wrinkle formation.
Methods :To investigate in vitro anti-oxidant activity assay, ethanol extracts of medicinal plants tested by DPPH method. In the next experiment, to investigate anti-inflammatory test, the RAW 264.7 macrophage cells was cultured using DMEM including the 10% FBS. To study anti-allergic effect, we blended cultured Human Mast Cells(HMC-1), and then observe TNF-α, IL-8 by ELISA
Results :Polygonum Cuspidatum extract has the effects of anti-inflammation and anti-allergy, which may be due to its inhibitory potential on the macrophage activation. Furthermore, Polygonum Cuspidatum extract has the anti-wrinkle effects through the inhibitory potential on the collagnease, elastase and gelatinase activities.
Conclusion :The above results suggest that Polygonum Cuspidatum extract could be applicable for improvement of several skin functions.
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KEYWORD
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Polygonum cuspidatum, Anti-oxidant, Anti-inflammation, Anti-allergy, Skin function
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